Cell Culture Media, Supplements, and Reagents
Sigma Aldrich Fine Chemicals Biosciences Thiamphenicol | 15318-45-3 | MFCD00467983 | 5G
Thiamphenicol | Mol Wt: 356.22 | 15318-45-3 | MFCD00467983 | 5G
Apexbio Technology LLC Neomycin sulfate(Synonyms: Neomycin sulphate, Fradiomycin sulfate, Neomycin trisulfate salt hydrate, Neosulf), 10g, CAS: 1405-10-3.
Neomycin sulfate (CAS 1405-10-3) is an aminoglycoside antibiotic that interacts with nucleic acid structures and ion channels influencing several biological processes It inhibits hammerhead ribozyme cleavage reactions by preferentially stabilizing the ribozyme-substrate ground-state complex thereby impeding catalytic turnover In HIV-1 research neomycin disrupts the interaction between Tat protein and the viral RNA TAR element via an allosteric noncompetitive mechanism Additionally neomycin binds specifically to DNA triplex structures particularly stabilizing TAT triplets It also demonstrates voltage- and concentration-dependent blockage of ryanodine receptor channels mainly from the luminal side These properties make neomycin sulfate valuable for mechanistic studies involving RNA/DNA structure interactions and channel functions
eMolecules 1642300-52-4 | Eltanexor (KPT-8602) | Selleck Chemicals | 428.298 | C17H10F6N6O | NC(=O)C(=Cn1cnc(n1)-c1cc(cc(c1)C(F)(F)F)C(F)(F)F)c1cncnc1 | 5mg | 351295167
Ambeed | Fmoc-Dab(Dde)-OH | 5g | 589944462 | A387609 | 235788-61-1 | MFCD11111552 | 504.583 | C29H32N2O6
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Medchemexpress LLC HY-114277 5mg Medchemexpress, AMG-510 CAS:2296729-00-3 Purity:>98%
Medchemexpress, HY-114277 5mg AMG-510 CAS:2296729-00-3 AMG-510 is a first-in-class, orally bioavailable, and selective KRAS G12C covalent inhibitor. AMG-510 irreversibly inhibits KRAS G12C by locking it in an inactive GDP-bound state. AMG-510 is the first KRAS G12C inhibitor in clinical development and leads to the regression of KRAS G12C tumors[2]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-15144 2mg Medchemexpress, Trichostatin A CAS:58880-19-6 Purity:>98%
Medchemexpress, HY-15144 2mg Trichostatin A CAS:58880-19-6 Trichostatin A (TSA) is a potent and specific inhibitor of HDAC class I/II, with an IC50 value of 1.8 nM for HDAC. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
eMolecules 937039-45-7 | N1-(2-Aminophenyl)-N7-(p-tolyl)heptanediamide | MFCD17010287 | 100mg
Ambeed | N1-(2-Aminophenyl)-N7-(p-tolyl)heptanediamide | 100mg | 552699098 | A301260 | 937039-45-7 | MFCD17010287 | 339.439 | C20H25N3O2
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Medchemexpress LLC CRAC intermediate 1 | 1249343-86-9 | 98.5% | 223.18 | 100 MG
CRAC intermediate 1 is a key intermediate in the chemical synthesis of a series of CRAC channel inhibitors. It is utilized in research related to inflammation and immune system diseases, and studies involving CRAC channels and calcium release-activated channels.
- Intermediate for chemical synthesis
- Used in research for CRAC channel inhibitors
- Relevant to inflammation and immune system disease studies
- Supports research on calcium release-activated channels
eMolecules 31430-18-9 | Nocodazole | MFCD00005588 | 1g
AstaTech | N24-TRIMETHYL-BENZENEMETHANAMINE | 0.25g | 448274766 | C78452 | 97.000 | 766502-85-6 | MFCD06655726 | 149.237 | C10H15N
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eMolecules 1450929-77-7 | Medchem Express | LHF-535 | 5mg | 459606858 | HY-112762 | 412.533 | C27H28N2O2
Ambeed | Fmoc-Cys(Et)-OH | 5g | 524986311 | A101966 | 200354-34-3 | MFCD00151921 | 371.450 | C20H21NO4S
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AdipoGen Puromycin . dihydrochloride ,Chemical. CAS: 58-58-2
Puromycin . dihydrochloride , AdipoGen Life Sciences. Chemical. CAS: 58-58-2. Formula: C22H29N7O5 . 2HCl. MW: 471.5 . 72.9. Isolated from Streptomyces alboniger. Aminonucleoside antibiotic. Protein synthesis inhibitor. Disrupts peptide transfer on ribosomes (acting as an acyl-tRNA analog) causing premature chain termination during translation. Translational inhibitor in prokaryotic and eukaryotic cells in both in vitro and in vivo systems. Inhibits the transport of proteins into the mitochondria in vitro. Reversible inhibitor of dipeptidyl-peptidase II (serine peptidase) and cytosol alanyl aminopeptidase (metallopeptidase). Apoptosis inducer. Inhibits the growth of Gram-positive bacteria, various animal and insect cells. Fungi and Gram-negative bacteria are resistant due to the low permeability to the antibiotic. Antineoplastic agent. Used in cell biology as selective agent in cell culture systems.
Sigma Aldrich Fine Chemicals Biosciences Vancomycin hydrochloride from Streptomyces orientalis, 1404-93-9, MFCD03613611, 250 mg
Empirical Formula (Hill Notation): C66H75Cl2N9O24 · HCl, Molecular Weight: 1485.71, potency: ≥900 μg per mg (as vancomycin base), storage temp: 2-8°C.
Sigma Aldrich Fine Chemicals Biosciences Dutasteride for system suitability European Pharmacopoeia (EP) Reference Standard | 164656-23-9 | MFCD00937869 |
Dutasteride for system suitability European Pharmacopoeia (EP) Reference Standard | Mol Wt: 528.53 | 164656-23-9 | MFCD00937869 |
Medchemexpress LLC N-(4-mesitylthiazol-2-yl)benzamide | 1001753-24-7 | 99.5% | 322.42 | C19H18N2OS | 25 MG
INH6 is a small-molecule Nek2/Hec1 inhibitor that inactivates Hec1/Nek2 function via protein degradation, leading to chromosome missegregation and cell death. It inhibits HeLa cell growth with an IC50 of 2.4 μM and produces mitotic defects and apoptosis in treated cells.
- Potent Nek2/Hec1 inhibition (IC50 2.4 μM).
- Inactivates Hec1/Nek2 through protein degradation, causing chromosome missegregation.
- Induces mitotic defects and apoptosis in cultured cells (~20% apoptotic cells at 72 h).
- Solid, white to off-white powder; soluble in DMSO (50 mg/mL) and in 10% DMSO/90% corn oil for animal dosing.
- Stable as powder at -20°C (3 years) and 4°C (2 years); in solvent stability varies by temperature.
![eMolecules 53123-88-9 | Rapamycin | Oakwood Chemical914.187 | C51H79NO13 | 98.000 | CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1O | 1g | 714320210](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000489061.jpg-250.jpg)
eMolecules 53123-88-9 | Rapamycin | Oakwood Chemical914.187 | C51H79NO13 | 98.000 | CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1O | 1g | 714320210
Rapamycin | Oakwood Chemical | 53123-88-9914.187 | C51H79NO13 | 98.000 | CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1O | 1g | 714320210
Cayman Chemical hygroscopIcus RapamycIn 10mg
An allosteric inhibitor of mTORC1; inhibits growth of Rh1 and Rh30 rhabdomyosarcoma cells in serum-free medium, with 50% inhibition observed at 0.1 and 0.5 ng/ml, respectively, and increases apoptosis in these cells at 100 ng/ml; induces autophagy in a variety of cell types; inhibits IL-2-induced proliferation of IL-2-dependent T cells by 50% at <5 pM